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    Risk of acute myocardial infarction among new users of chondroitin sulfate: A nested case-control study - PubMed
    December 9, 2025 at 10:06:32 AM PST * - permalink - archive.org -
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    - https://pubmed.ncbi.nlm.nih.gov/34252115/
    chondroitin_sulfate heart_disease
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    The Side of Andor That Nobody Talks About - YouTube
    December 8, 2025 at 9:18:13 PM PST * - permalink - archive.org -
    QRCode
    - https://www.youtube.com/watch?v=ZYDb9V9ZZjA
    Andor
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    A Statistical Error in the Estimation of the Recommended Dietary Allowance for Vitamin D - PMC

    The paper argues that the Institute of Medicine (IOM) made a statistical mistake when deriving the Recommended Dietary Allowance (RDA) for vitamin D, so 600 IU/day does not, in fact, ensure adequate vitamin D status for 97.5% of individuals.[1]

    Core claim

    The IOM intended the vitamin D RDA to be the intake that gives at least 50 nmol/L of serum 25(OH)D in 97.5% of healthy people, and set this at 600 IU/day based on pooled supplementation studies at high latitudes in winter. The authors show that the IOM actually used a prediction interval for study means, not for individuals, so the 600 IU figure only predicts that 97.5% of future study averages exceed about 50 nmol/L, not that 97.5% of people do.[1]

    Corrected statistical interpretation

    Using the eight trials that reported both mean and standard deviation, the authors reconstructed the lower tail (about the 2.5th percentile) of individual 25(OH)D values at each dose by subtracting two standard deviations from the mean. Regressing these reconstructed 2.5th percentiles on vitamin D intake showed that 600 IU/day would give 97.5% of individuals a level above only about 26.8 nmol/L, not 50 nmol/L.[1]

    Implications for required intake

    Extrapolating the same regression, the intake needed so that 97.5% of individuals reach at least 50 nmol/L is estimated at roughly 8900 IU/day, well above both the current RDA (600 IU) and the IOM’s tolerable upper intake level of 4000 IU/day. The authors stress that this estimate lies outside the range of doses actually studied, so it should be interpreted cautiously, but it clearly implies the true requirement is far above 600 IU/day.[1]

    Public health impact

    The authors point to Canadian data, where background diet provides about 232 IU/day, showing that even with supplements of 400 IU or more (total ≥632 IU/day), 10–15% of adults still have 25(OH)D below 50 nmol/L. If the RDA were correctly set for 97.5% coverage, fewer than 2.5% should fall below this threshold, so these observations empirically support the claim that the current RDA is too low.[1]

    Recommendation

    Because the misinterpretation leads to underestimation of vitamin D needs, the authors conclude that the vitamin D RDA should be revisited so that public health guidance and clinical decisions are based on requirements of individuals rather than study averages. They argue that without such correction, goals related to bone health and prevention of vitamin D–related disease cannot be reliably met.[1]

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    December 8, 2025 at 8:47:47 PM PST * - permalink - archive.org -
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    - https://pmc.ncbi.nlm.nih.gov/articles/PMC4210929/
    Vitamin_D
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    Vitamin D mistake

    https://pmc.ncbi.nlm.nih.gov/articles/PMC4210929/

    The reanalysis paper suggests that, to get about 97.5% of people to at least 20 ng/mL (50 nmol/L), an intake around 8,900 IU/day would be needed, which is far above current official recommendations. However, major medical bodies still advise much lower routine doses and treat such high intakes as above the usual safe upper limit.[1][2][3][4][5]

    What the reanalysis suggests

    • Using the same data the Institute of Medicine used, the statisticians estimated that about 8,895 IU/day would be required so that 97.5% of individuals reach at least 50 nmol/L (20 ng/mL).[3][1]
    • This is roughly 10–15 times higher than the current RDA of 600 IU/day for most adults, which they argue is the result of a statistical miscalculation.[4][1]

    What official bodies recommend

    • The Institute of Medicine (now the National Academies) RDA is 600 IU/day for adults up to 70 and 800 IU/day for those over 70, with a tolerable upper intake level of 4,000 IU/day.[4]
    • The Endocrine Society suggests that many adults may need 1,500–2,000 IU/day to keep blood levels consistently above about 30 ng/mL (75 nmol/L), which they consider a preferable minimum.[2][5]

    Practical takeaways

    • The “8,900 IU” figure is an argument that the true RDA (to cover almost everyone) is much higher than current guidelines, not a blanket dose recommendation for individuals.[1][3]
    • In practice, most mainstream advice lands around 1,000–2,000 IU/day as a generally safe supplement dose for adults, with higher doses reserved for people monitored by a clinician who is checking blood 25‑OH vitamin D levels and other risk factors.[6][5]

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    December 8, 2025 at 8:45:38 PM PST * - permalink - archive.org -
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    - https://rumble.com/v72qdha-vitamin-d-mistake.html?e9s=src_v1_eh_cs
    John_Campbell Vitamin_D
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    All Dremel Rotary Tool Models Explained: Buyers Guide - YouTube
    December 6, 2025 at 7:42:31 PM PST * - permalink - archive.org -
    QRCode
    - https://www.youtube.com/watch?v=G56VSt3nJoQ&t=238s
    Dremel
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    Elizabeth Dulau: The Untold Truth Behind Andor’s Most Mysterious Rebel | Star Fun Facts - YouTube
    December 6, 2025 at 12:54:56 PM PST * - permalink - archive.org -
    QRCode
    - https://www.youtube.com/watch?v=YhSg9t-FGPU
    Elizabeth_Dulau Andor
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    Flying After 60: 10 FEDERALLY Protected Rights Airlines Hope You Never Claim - YouTube

    The video explains 10 key air travel rights for seniors and travelers with disabilities under the Air Carrier Access Act (ACAA) and related rules, focusing on the exact language to use so airlines must honor them.

    Hidden discounts and security help

    • Some major airlines still offer “senior fares” (often 65+) that are not shown online; you usually must call reservations and specifically ask them to check for a “senior fare” on your route and compare it to online prices.
    • TSA Cares offers a free “passenger support specialist” who can meet you and personally guide you through security if you have a disability, medical device, or high anxiety, as long as you contact them about 72 hours before travel.

    Free better seating and escorts

    • If you need an aisle, bulkhead, or extra-legroom seat for a medical or mobility reason, you can request it as a disability accommodation using “I require…” language rather than as a preference, and a required care companion must be seated with you at no extra charge.
    • “Guided assistance” or “meet and assist” is a free right, not a paid perk: an escort can take you from check-in through security to the gate, onto the plane, and after landing to baggage claim and the curb, and this can also be used to get a family member an escort pass to go through security with you.

    Medical bags, screening, and pre-boarding

    • Assistive devices and medical equipment (CPAPs, mobility aids, medication coolers, etc.) are exempt from baggage fees and do not count toward your normal luggage allowance, and agents cannot demand prescriptions or make you power devices on.
    • Travelers 75+ get “modified screening,” meaning they can usually keep shoes and light jackets on and can request to sit for pat-downs; they should notify TSA about implants or devices and can use a doctor-provided notification card.
    • Any passenger with a qualifying physical or mental impairment (including common age-related mobility issues) has a right to pre-boarding before all other groups by simply self-identifying at the gate and asking for pre-boarding as an accommodation.

    Cancellations, tarmac delays, and priority

    • When there are delays or cancellations (“irregular operations”), passengers with documented assistance needs are supposed to be prioritized for manual rebooking and support, including hotel, transport, and meal vouchers when the airline (not weather) is at fault.
    • In tarmac delays, airlines generally must let domestic passengers off by 3 hours (4 for international) and must provide food and water after 2 hours, with working accessible restrooms; those with medical needs can request water or snacks sooner to take medication.

    Escalation “nuclear options”

    • If staff deny a reasonable accommodation, you can ask for a Complaint Resolution Official (CRO), a legally required specialist supervisor trained in the ACAA, which usually prompts quick compliance.
    • After travel, you can file an official U.S. Department of Transportation complaint via its web form using language that the airline failed to provide a reasonable accommodation under the ACAA, which forces a written response and puts the issue on the airline’s record.

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    December 6, 2025 at 8:40:40 AM PST * - permalink - archive.org -
    QRCode
    - https://www.youtube.com/watch?v=8z4Pi53NwXg
    airplane travel
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    How Critical Role's DM Solved D&D Prep - YouTube

    For all three toy types, you can use the same ultra‑generic trio: motivation, relationship, and immediate problem. Motivation is “why this thing exists or acts,” relationship is “who or what it is most connected to,” and immediate problem is “what is happening right now that stresses or changes it.”[1][2]

    Single template for all toys

    Use this same three‑part template, regardless of whether it is a character, location, or situation.[2][3]

    • Motivation: What this person/place/event is fundamentally trying to do or be (their purpose or goal).
    • Relationship: The most important link it has to someone or something else (faction, NPC, PC, resource, belief).
    • Immediate problem: The current, time‑sensitive issue colliding with that motivation and relationship in this moment.

    How it maps per type

    Applying the same three requirements keeps prep minimal but rich.[4][2]

    • Character: Motivation (goal), relationship (who they care about or serve), immediate problem (today’s crisis).
    • Location: Motivation (why it exists / its function), relationship (who uses or controls it), immediate problem (what is going wrong here now).
    • Situation: Motivation (the outcome the situation is driving toward), relationship (which parties are bound up in it), immediate problem (the current flashpoint or ticking clock).

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    December 6, 2025 at 7:50:07 AM PST * - permalink - archive.org -
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    - https://www.youtube.com/watch?v=q-kLrzn_Ebk
    DnD DM Brennan_Lee_Mulligan
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    Why Scandinavian Cabins Stayed Warm At -30°F While Modern Homes Freeze - YouTube

    The video explains that traditional Scandinavian log cabins stayed comfortably warm for days in subzero temperatures because they were built as “thermal batteries” using dense wood, extreme airtightness, and radiant masonry heaters, while many modern homes lose heat rapidly once the furnace stops.[1]

    Key experiment and finding

    A modern, highly insulated prefab house and a reconstructed medieval log cabin were heated to about 68°F and then had their heat cut at around -8°F outside. The modern house fell close to freezing within hours, while the log cabin stayed above freezing for about three days, showing that thermal mass and airtightness mattered more than high insulation R-value alone in this scenario.[1]

    Three core principles

    The video highlights three main reasons old cabins perform so well: high thermal mass, near-absolute airtightness, and a heating strategy that stores heat in mass instead of constantly heating air. Dense, slow-grown logs act as large heat reservoirs, tight joinery plus moss and clay seals stop drafts, and masonry heaters or soapstone stoves store a short, hot fire’s energy and radiate it for 12–18 hours.[1]

    Design details that save heat

    Cabins used small, compartmentalized rooms with low ceilings, thick plank floors insulated with sawdust or moss, and stone piers lifting the structure off the cold ground to avoid concrete “thermal bridges” into the soil. This “thermal zoning” kept main living spaces warm while allowing bedrooms to run cooler under heavy bedding, reducing total heating demand.[1]

    Why modern building went wrong

    Modern construction shifted to light stick framing, fiberglass insulation, vapor barriers, and forced-air systems because this was faster and cheaper when energy was inexpensive. Many newer homes are leaky, have little thermal mass, and depend on continuous fuel or electricity, making them fragile in blackouts despite meeting code insulation targets.[1]

    How to apply the lessons today

    The video suggests modern homes can regain resilience by using mass timber or interior stone elements, focusing on airtightness with blower-door testing and meticulous sealing, and using radiant or masonry-style heating where possible. It also recommends compact layouts over vaulted open plans and evaluating cost over the full life of the building, noting that solid-wood and mass-heavy designs can use far less energy and stay livable longer during power outages.[1]

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    December 5, 2025 at 9:57:39 PM PST * - permalink - archive.org -
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    - https://www.youtube.com/watch?v=eVqwiMtoDhk
    construction
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    6 Rules That Will Make Your Car Last 300,000 Miles - A Parts Guy's Maintenance Schedule. - YouTube

    The video lays out six practical maintenance rules designed to help a typical car reach 250,000–300,000 miles without becoming a money pit.[1]

    Core message

    Chris, a longtime auto parts counter worker, argues that most cars die early because of poor maintenance habits and overly optimistic factory intervals, not because they are “worn out” at 150,000 miles. He then gives a conservative, real‑world schedule for fluids and filters that prioritizes engine and transmission longevity over stretching service intervals.[1]

    Six maintenance rules

    1. Use quality synthetic oil and filter

      • Always run full synthetic oil and a high‑quality oil filter, not the cheapest conventional options.[1]
      • Change intervals depend on use: 3,000–4,000 miles for short trips/hot climates, around 5,000 for mixed driving, and never more than 3,000 with cheap oil and filters.[1]
    2. Replace engine air filter often

      • Treat the engine air filter as critical for engine “breathing,” changing it every other oil change, or every oil change in dusty, hot, or heavy‑traffic environments.[1]
      • A clogged filter can skew fuel trims rich, increase carbon buildup and combustion temperatures, hurt fuel economy, and stress rings and the catalytic converter.[1]
    3. Use Top Tier fuel and avoid low tank levels

      • Always choose Top Tier gasoline brands with higher detergents (e.g., major-name stations, including warehouse clubs like Costco).[1]
      • He adds a “bonus rule”: never let the tank drop below a quarter, because fuel cools and lubricates the pump, and running low overheats and shortens pump life.[1]
    4. Run a PEA-based injector cleaner regularly

      • Use a polyetheramine (PEA)–based fuel injector cleaner every 5,000–7,000 miles, or at each oil change.[1]
      • PEA products can dissolve baked-on carbon and restore a fine spray pattern, preventing hot spots, misfires, poor mileage, and unstable combustion temperatures.[1]
    5. Change transmission fluid early, not after problems

      • Replace automatic transmission fluid about every 50,000–60,000 miles for normal use, and 30,000–40,000 miles for heavy city driving, towing, or delivery work.[1]
      • Once fluid breaks down, it forms varnish, sticks solenoids, burns clutch packs, and causes slipping and harsh shifts; by the time symptoms appear, damage is usually already done.[1]
    6. Flush coolant every 3–5 years

      • Ignore “100,000‑mile” or “lifetime” coolant claims and flush coolant every 3–5 years.[1]
      • As coolant ages, additives deplete, corrosion starts, pH shifts, aluminum parts are attacked, heat transfer worsens, and even one serious overheat can remove tens of thousands of miles from an engine’s life.[1]

    Overall takeaway

    These rules are presented as conservative, real‑world intervals based on what the creator sees failing at the parts counter, not on marketing claims or minimal factory schedules. The main idea is that relatively inexpensive, proactive fluid and filter maintenance dramatically improves the odds of a car reaching 250,000–300,000 miles without major failures.[1]

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    December 5, 2025 at 7:45:22 AM PST * - permalink - archive.org -
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    - https://www.youtube.com/watch?v=8Ote9sLF0Jw
    maintenance auto
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    Honest Trailers | Andor (Season 2) - YouTube
    December 4, 2025 at 10:33:12 PM PST * - permalink - archive.org -
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    - https://www.youtube.com/watch?v=vAKMEcVcoFQ
    Andor
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    Tony Gilroy: Andor Explains America's Dark Moment - YouTube
    December 4, 2025 at 10:16:29 PM PST * - permalink - archive.org -
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    - https://www.youtube.com/watch?v=iaqnHfa6n4E
    Tony_Gilroy Andor
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    ANDOR'S Elizabeth Dulau & Pierro Niel-Mee Talk Star Wars, Theatre, Tony Gilroy's Script, and more - YouTube
    December 4, 2025 at 7:25:10 PM PST * - permalink - archive.org -
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    - https://www.youtube.com/watch?v=TDj08GBGd-k
    Andor Elizabeth_Dulau
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    Andor Season 2: The Biggest Twist Is Hiding In Plain Sight | Star Wars Explained - YouTube

    @1chrisford
    5 months ago
    "I know Kleya was not written as the main person behind the Rebellion because of how she was cast and used. She was Luthen's right hand man who did not have many lines. The quite competent apprentice. The actress cast for the part was not the 1st or 2nd choice. Just graduated from Drama school.. The suits said they wanted experience given the money invested. She moved on, tried to get other parts, wasn't working - gets a call out of the blue from the highly rated casting agent Nina Gold, who saw her, Elizabeth Dulau as gifted. She impressed Stellan when doing the casting reading with him. Got the part. Then feedback from Skarsgard and Season 1 directors got to Gilroy and said Dulau was killing the scenes had had a serious presence, rare in someone her age.
    So Kleya was written as a key character for Season 2. It was a great choice by the showrunner. And Stellan as advocate for making Kleya core to the backstory of Rael. And showing again, through the scenes Gilroy created for her - the cost of rebellion after she killed him.

    She was the able apprentice that helped make Luthen and Rael a successful, powerful team.
    But remember, it was always supposed to be Luthen as boss.
    Kleya was written the adept sidekick to the Master. Robin to Batman. Then elevated in Season 2. To the end, Luthen was in charge.He ORDERED her to go to the safehouse and get the message out. He would likely die as the Empire closed in on the antiquities shop any moment.

    Andor was filled with top acting and characters. Elizabeth Dulau earned a place there for her and KLeya.
    Take a bow, Elizabeth. Her performance as Kleya helped elevate Kleya into Star Wars canon"

    December 4, 2025 at 6:18:41 PM PST * - permalink - archive.org -
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    - https://www.youtube.com/watch?v=JWKw2ZqeHTc
    Andor Elizabeth_Dulau
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    Showrunner Tony Gilroy Dives Deep on ANDOR | Creating Cultures, Enriching Cannon, & a Hopeful Ending - YouTube
    December 3, 2025 at 7:57:12 PM PST * - permalink - archive.org -
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    - https://www.youtube.com/watch?v=21FS7CVClxo
    Andor Tony_Gilroy
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    How to Survive a Heart Attack Alone After 60 - 7 Life Saving Tips Every Senior Must Know! - YouTube
    December 3, 2025 at 7:02:15 PM PST * - permalink - archive.org -
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    - https://www.youtube.com/watch?v=fVeoWIAvLFc
    heart_attack
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    Andor Season 2 Declassified: Farewell | Contains Spoilers Eps 10-12 - YouTube
    December 3, 2025 at 2:49:53 PM PST * - permalink - archive.org -
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    - https://www.youtube.com/watch?v=B-sI-Iz_zyo
    Andor
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    Genevieve O’Reilly and Faye Marsay on Andor, ambition and giving Mon Mothma a voice - YouTube

    Faye Marsay

    December 3, 2025 at 1:45:59 PM PST * - permalink - archive.org -
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    - https://www.youtube.com/watch?v=vRRIkfwj5So
    Faye_Marsay Genevieve_O'Reilly Andor
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    Andor's Tony Gilroy Reveals Which Season 2 Plotline He Had To Really Sell To Make Happen - YouTube
    December 3, 2025 at 12:34:17 PM PST * - permalink - archive.org -
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    - https://www.youtube.com/watch?v=2LvjG6JGkgw
    Andor Tony_Gilroy Genevieve_O'Reilly
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    Andor: Kleya Marki - YouTube

    Elizabeth Dulau

    December 3, 2025 at 12:06:43 PM PST * - permalink - archive.org -
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    - https://www.youtube.com/watch?v=Eo99rrgCuls
    Elizabeth_Dulau Andor
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